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Stroke and Cerebrovascular Syndromes

Manual: General · Subject: Neurology

Master the vascular logic behind ischemic and hemorrhagic stroke presentation, diagnosis, and acute treatment.

Vascular Anatomy and Stroke Logic

Territories matter

Stroke syndromes often follow arterial territories. Recognizing the pattern helps predict deficits, guide imaging, and determine whether a large vessel is involved.

Common vascular territories

TerritoryTypical deficits
MCAFace and arm weakness, aphasia or neglect, visual field loss
ACALeg weakness, abulia, frontal signs
PCAVisual field deficits, memory or visual processing problems
Brainstem perforatorsCranial nerve deficits with long-tract signs
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Time is brain

Acute stroke evaluation is driven by rapid recognition, urgent brain imaging, and fast treatment decisions.

Sudden right face and arm weakness with aphasia most strongly suggests infarction in the left:

What is the key initial imaging study for suspected acute stroke in most emergency settings?

Ischemic Stroke Mechanisms

Major ischemic mechanisms

Thrombotic/atherosclerotic

  • Large-artery disease
  • May have preceding transient ischemic attacks

Embolic

  • Sudden onset with maximal deficit at onset
  • Often from atrial fibrillation or cardiac source

Which mechanism is most associated with an abrupt maximal deficit at onset and a cardiac source?

Name one common risk factor for lacunar infarction.

Hemorrhage and Secondary Prevention

When bleeding matters

Intracerebral hemorrhage and subarachnoid hemorrhage require different diagnostic and management priorities than ischemic stroke. Blood pressure control, reversal of coagulopathy, and neurosurgical evaluation may be critical.

Severe thunderclap headache with meningeal signs raises concern for:

Why is atrial fibrillation important in stroke prevention?